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Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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IL-1β delivers a sweet deal

February 15, 2017

Interleukin 1β (IL-1β) is a cytokine associated with inflammation, obesity and metabolic dysregulation. Surprisingly, IL-1β is also required for maintaining steady-state glucose homeostasis by...

Innate B cells cleave to the marginal zone

February 15, 2017

The kinase Taok3 and protease ADAM10 mediate determination of the fate of marginal zone B cells.

Anti-dengue IgG1

February 15, 2017

Keeping skin inflammation local

February 15, 2017

Silencing of the chromatin remodeler Mi-2β in keratinocytes triggers local skin inflammation. Regulatory T cells activated by the cytokine TSLP control the shift from local skin inflammation to...