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Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

Dr. Laurence Morel

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Select Publications

Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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Metastasis factor

September 18, 2015

Subversion of anticancer immunosurveillance by radiotherapy

September 18, 2015

Paradoxically, radiotherapy can reinforce immunosuppressive pathways that undermine anticancer immunosurveillance and treatment efficacy. Irradiation induces Langerhans cells to migrate from the skin...

Autophagy and autophagy-related proteins in the immune system

September 18, 2015

Autophagy is an essential intracellular degradation process. Yoshimori and colleagues review the broad role of autophagy in immunological function.

To κ+ B or not to κ+ B

September 18, 2015

Immature B lymphocytes and T lymphocytes assemble antigen receptor–encoding genes in lineage- and developmental stage–specific fashion. New findings show that pre-B cells use specialized...