Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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Breathe easy with neutrophils

October 18, 2017

Breathe easy with neutrophilsNature Immunology, Published online: 18 October 2017; doi:10.1038/ni.3864

CD28 enhances mitochondrial function

October 18, 2017

CD28 enhances mitochondrial functionNature Immunology, Published online: 18 October 2017; doi:10.1038/ni.3860

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

October 18, 2017

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetesNature Immunology, Published online: 18 October 2017; doi:10.1038/ni1117-1271c

Corrigendum: The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation

October 18, 2017

Corrigendum: The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammationNature Immunology, Published online: 18 October 2017; doi:10.1038/ni1117-1271a

FoxP3 partners up

October 18, 2017

FoxP3 partners upNature Immunology, Published online: 18 October 2017; doi:10.1038/ni.3852By switching its partners, FoxP3 segregates into functional and non-functional transcriptional complexes.