Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells

November 21, 2017

Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cellsSingle-cell analysis reveals the continuum of human lympho-myeloid progenitor cells, Published online: 21 November...

Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells

November 21, 2017

Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cellsAtad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor...

Nuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNA

November 21, 2017

Nuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNANuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNA,...

Inflammatory lipids

November 16, 2017

Inflammatory lipidsInflammatory lipids, Published online: 16 November 2017; doi:10.1038/ni.3876Inflammatory lipids

Feeling stressed? It might be your T cells

November 16, 2017

Feeling stressed? It might be your T cellsFeeling stressed? It might be your T cells, Published online: 16 November 2017; doi:10.1038/ni.3872Abolishing signals mediated by the inhibitory receptor PD-1...