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Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

Dr. Laurence Morel

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Select Publications

Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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TET1: an epigenetic guardian of lymphomagenesis

May 19, 2015

Due to their role in regulating DNA-methylation patterns, the TET proteins, in particular TET2, have emerged as key participants in tumorigenesis. Now the spotlight shifts to TET1 and its role as a...

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

May 19, 2015

HIV devotes a large portion of its coding capacity to counteracting the function of mammalian antiviral proteins. Landau and colleagues discuss the biology of mammalian restriction factors and the...

Innate immunity against HIV-1 infection

May 19, 2015

Innate effector mechanisms contribute to the control of viremia and modulate the quality of the adaptive immune response to HIV-1. Altfeld and Gale discuss the concerted actions of PRR signaling,...