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Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

Dr. Laurence Morel

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Select Publications

Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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Development of innate lymphoid cells

June 21, 2016

Innate lymphoid cells (ILCs) arise from distinct hematopoietic progenitors. Zook & Kee discuss the transcriptional programs that direct the development of natural killer cells and various ILC...

A versatile cell population

June 21, 2016

Innate lymphoid cells serve multiple roles in maintaining tissue homeostasis and responding to tissue insults and can contribute to chronic inflammatory diseases.

Family ties among CNS macrophages

June 21, 2016

Perivascular and subdural meningeal macrophages at the interface between the central nervous system and the periphery are self-renewing and arise from early embryonic precursors. Macrophages residing...

Bach2 is required for B cell and T cell memory differentiation

June 21, 2016

B cell and T cell memory differentiation requires the transcription factor Bach2, which inhibits the effector-cell fate by limiting antigen-receptor-stimulation-induced gene expression and restricting...