Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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Author Correction: The cellular composition of the human immune system is shaped by age and cohabitation

November 25, 2020

Nature Immunology, Published online: 25 November 2020; doi:10.1038/s41590-020-00839-4Author Correction: The cellular composition of the human immune system is shaped by age and cohabitation

Establishment of an African green monkey model for COVID-19 and protection against re-infection

November 24, 2020

Nature Immunology, Published online: 24 November 2020; doi:10.1038/s41590-020-00835-8Geisbert and colleagues report that African green monkeys infected with the SARS-CoV-2 virus develop disease...

MEK inhibition reprograms CD8<sup>+</sup> T lymphocytes into memory stem cells with potent antitumor effects

November 23, 2020

Nature Immunology, Published online: 23 November 2020; doi:10.1038/s41590-020-00818-9Stem cell–like memory (TSCM) CD8+ T cells are beneficial in antitumor responses, in part due to their ability to...

Author Correction: A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma

November 19, 2020

Nature Immunology, Published online: 19 November 2020; doi:10.1038/s41590-020-00841-wAuthor Correction: A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma

Author Correction: Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function

November 19, 2020

Nature Immunology, Published online: 19 November 2020; doi:10.1038/s41590-020-00843-8Author Correction: Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function