Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection

March 5, 2021

Nature Immunology, Published online: 05 March 2021; doi:10.1038/s41590-021-00902-8The contribution of T cells to the SARS-CoV-2 response remains an important and unresolved question. Moss and...

Wnt–β-catenin activation epigenetically reprograms T<sub>reg</sub> cells in inflammatory bowel disease and dysplastic progression

March 4, 2021

Nature Immunology, Published online: 04 March 2021; doi:10.1038/s41590-021-00889-2Gounari and colleagues examine how the Wnt–β-catenin signaling axis in regulatory T cells promotes inflammatory...

Publisher Correction: Fiber-poor Western diets fuel inflammation

March 4, 2021

Nature Immunology, Published online: 04 March 2021; doi:10.1038/s41590-021-00907-3Publisher Correction: Fiber-poor Western diets fuel inflammation

Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8<sup>+</sup> T cells

March 3, 2021

Nature Immunology, Published online: 03 March 2021; doi:10.1038/s41590-021-00906-4Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells

Effector and stem-like memory cell fates are imprinted in distinct lymph node niches directed by CXCR3 ligands

March 1, 2021

Nature Immunology, Published online: 01 March 2021; doi:10.1038/s41590-021-00878-5T cells are highly dynamic and their spatial and cellular interactions can influence their differentiation program....