Drugs for Metabolism Could Reverse Lupus

The study performed by the Morel Laboratory  provides compelling evidence that a combination of metabolic inhibitors could be an effective lupus therapy

A Clear Direction

Dr. Laurance Morel is the Director of the Experimental Pathology division at UF’s College of Medicine

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Lupus resistance is associated with marginal zone abnormalities in an NZM murine model

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Sometimes, it’s Lupus

Fictional character Dr. House is famous for proclaiming “It’s not Lupus,” but with 5 million Americans suffering from Lupus, it is certainly not an uncommon disease by an stretch of the imagination.

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CD4<sup>+</sup> T cell signatures in HIV infection

July 15, 2019

Nature Immunology, Published online: 15 July 2019; doi:10.1038/s41590-019-0447-5Analysis of the whole-genome transcriptional activity of HIV-specific CD4+ T cells demonstrates distinct profiles...

Early childhood education is critical for T<sub>reg</sub> cells

July 15, 2019

Nature Immunology, Published online: 15 July 2019; doi:10.1038/s41590-019-0440-zCharacterization of the self antigens that neonatal regulatory T cells recognize reveals dramatic effects of age and...

At the end of the beginning: immunotherapies as living drugs

July 15, 2019

Nature Immunology, Published online: 15 July 2019; doi:10.1038/s41590-019-0452-8The American Course on Drug Development and Regulatory Science and the US National Institutes of Health held a workshop...

Altered differentiation is central to HIV-specific CD4<sup>+</sup> T cell dysfunction in progressive disease

July 15, 2019

Nature Immunology, Published online: 15 July 2019; doi:10.1038/s41590-019-0418-xHIV infection results in T cell dysfunction. Kaufmann and colleagues demonstrate that HIV infection results in an...

‘-Omics’ shed light on B cells in lupus

July 8, 2019

Nature Immunology, Published online: 08 July 2019; doi:10.1038/s41590-019-0446-6Epigenetic and transcriptional analyses of B cell subsets from patients with systemic lupus erythematosus reveal...