Wei Li

Wei Li

My areas of expertise are in the functional assays of immune cells, especially T cells from mouse and human. Our lab has previously shown that the lupus susceptibility gene, Esrrg was associated with the production of autoreactive CD4+ T cells together with the cell metabolic dysfunction in the Sle1c lupus susceptibility locus and lupus susceptibility in our Triple congenic (TC) mouse model. Currently, we have generated the CD4 and Foxp3 specific Esrrg-knock-out mice and I am studying on the function of Esrrg on T cells as well as its role in the cell metabolism. Also, I am trying to find metabolic inhibitors of immune cells, especially T cells in the lupus-prone mice.

 

liweigoodmorning@ufl.edu